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alpha-Pyrrolidinohexiophenone (PV-7alpha-PHPA-PHP, and α-PHP) is a lesser-known novel stimulant substance of the cathinone class. It is structurally related to compounds such as MDPV and is one of the successors of the designer drug cathinone analog α-PVP.

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A-PHP is commonly referred to as alpha-pyrrolidinyl-hexaphenone, PHP, and alpha-PHP. The IUPAC name for a-PHP is (±)-1-Phenyl-2-(1-pyrrolidinyl)-1-hexanone. We can look at the research conducted on this research chemical. ACD/Labs researched the US Environmental Protection Agency’s EPISuite and ChemAxon. Properties that ACD/Labs predicted showed two #H bond acceptors, five #Freely rotating bonds, an index of refraction at 1.535 with a surface tension of 39.3±3.0 dyne/cm, a flash point of 127.3±12.5 °C and a boiling point of 362.4±25.0 °C at 760 mmHg.

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α-PHP generally comes in fine powder or crystallized shards, which users can ingest to produce powerful but short-lived euphoric stimulant effects comparable to those of methamphetamine and cocaine when insufflated or vaporized. Like its research chemical cathinone predecessors, it has gained notoriety for its tendency to induce compulsive redosing and addictive behaviors in a large percentage of its users, as well as the ability to cause delusional states and psychosis when abused readily.

The mechanism of action of α-PHP is unknown. Aside from a substantially shorter duration, it is believed to act similarly to the designer drug pentedrone and α-PVP, which both as a potent norepinephrine-dopamine reuptake inhibitor (NDRI), although no substantial research on the pharmacology of this compound has yet been conducted.

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*Don’t take medicine if you are lactating, planning for pregnancy, or pregnant.
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*Keep this medicine away from the reach of pets, kids, and individuals with the same qualities.

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